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A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production.
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, Holtzman MJ. Keeler SP, et al. Among authors: romero ag. bioRxiv [Preprint]. 2023 Oct 4:2023.05.26.542451. doi: 10.1101/2023.05.26.542451. bioRxiv. 2023. PMID: 37292761 Free PMC article. Updated. Preprint.
Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.
Yurtsever Z, Sala-Rabanal M, Randolph DT, Scheaffer SM, Roswit WT, Alevy YG, Patel AC, Heier RF, Romero AG, Nichols CG, Holtzman MJ, Brett TJ. Yurtsever Z, et al. Among authors: romero ag. J Biol Chem. 2012 Dec 7;287(50):42138-49. doi: 10.1074/jbc.M112.410282. Epub 2012 Oct 30. J Biol Chem. 2012. PMID: 23112050 Free PMC article.
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
Alevy YG, Patel AC, Romero AG, Patel DA, Tucker J, Roswit WT, Miller CA, Heier RF, Byers DE, Brett TJ, Holtzman MJ. Alevy YG, et al. Among authors: romero ag. J Clin Invest. 2012 Dec;122(12):4555-68. doi: 10.1172/JCI64896. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187130 Free PMC article.
A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production.
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, Holtzman MJ. Keeler SP, et al. Among authors: romero ag. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L726-L740. doi: 10.1152/ajplung.00183.2023. Epub 2023 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37847710
24 results