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Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation.
Kemp SA, Collier DA, Datir R, Ferreira I, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N; CITIID-NIHR BioResource COVID-19 Collaboration; COVID-19 Genomics UK (COG-UK) Consortium; Sharrocks K, Blane E, Briggs J, van GM, Smith K, Bradley JR, Smith C, Doffinger R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth C, McCoy LE, Gupta RK. Kemp SA, et al. Among authors: goldstein ra. medRxiv [Preprint]. 2020 Dec 29:2020.12.05.20241927. doi: 10.1101/2020.12.05.20241927. medRxiv. 2020. PMID: 33398302 Free PMC article. Updated. Preprint.
Evolution of functionality in lattice proteins.
Williams PD, Pollock DD, Goldstein RA. Williams PD, et al. Among authors: goldstein ra. J Mol Graph Model. 2001;19(1):150-6. doi: 10.1016/s1093-3263(00)00125-x. J Mol Graph Model. 2001. PMID: 11381526 Free PMC article.
Amino acid coevolution induces an evolutionary Stokes shift.
Pollock DD, Thiltgen G, Goldstein RA. Pollock DD, et al. Among authors: goldstein ra. Proc Natl Acad Sci U S A. 2012 May 22;109(21):E1352-9. doi: 10.1073/pnas.1120084109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547823 Free PMC article.
Strong evidence for protein epistasis, weak evidence against it.
Pollock DD, Goldstein RA. Pollock DD, et al. Among authors: goldstein ra. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1450. doi: 10.1073/pnas.1401112111. Epub 2014 Mar 20. Proc Natl Acad Sci U S A. 2014. PMID: 24706894 Free PMC article. No abstract available.
Nonadaptive Amino Acid Convergence Rates Decrease over Time.
Goldstein RA, Pollard ST, Shah SD, Pollock DD. Goldstein RA, et al. Mol Biol Evol. 2015 Jun;32(6):1373-81. doi: 10.1093/molbev/msv041. Epub 2015 Mar 3. Mol Biol Evol. 2015. PMID: 25737491 Free PMC article.
The tangled bank of amino acids.
Goldstein RA, Pollock DD. Goldstein RA, et al. Protein Sci. 2016 Jul;25(7):1354-62. doi: 10.1002/pro.2930. Epub 2016 May 12. Protein Sci. 2016. PMID: 27028523 Free PMC article.
221 results