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Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor.
Skvara H, Kalthoff F, Meingassner JG, Wolff-Winiski B, Aschauer H, Kelleher JF, Wu X, Pan S, Mickel L, Schuster C, Stary G, Jalili A, David OJ, Emotte C, Antunes AM, Rose K, Decker J, Carlson I, Gardner H, Stuetz A, Bertolino AP, Stingl G, De Rie MA. Skvara H, et al. Among authors: meingassner jg. J Invest Dermatol. 2011 Aug;131(8):1735-44. doi: 10.1038/jid.2011.48. Epub 2011 Mar 24. J Invest Dermatol. 2011. PMID: 21430703 Free article. Clinical Trial.
Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.
Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T, Voshol H, Meingassner JG, Mao X, Werner G, Rot A, Carballido JM. Rubic T, et al. Among authors: meingassner jg. Nat Immunol. 2008 Nov;9(11):1261-9. doi: 10.1038/ni.1657. Epub 2008 Sep 28. Nat Immunol. 2008. PMID: 18820681
The PKC inhibitor AEB071 may be a therapeutic option for psoriasis.
Skvara H, Dawid M, Kleyn E, Wolff B, Meingassner JG, Knight H, Dumortier T, Kopp T, Fallahi N, Stary G, Burkhart C, Grenet O, Wagner J, Hijazi Y, Morris RE, McGeown C, Rordorf C, Griffiths CE, Stingl G, Jung T. Skvara H, et al. Among authors: meingassner jg. J Clin Invest. 2008 Sep;118(9):3151-9. doi: 10.1172/JCI35636. J Clin Invest. 2008. PMID: 18688284 Free PMC article. Clinical Trial.
Neutropenia with impaired immune response to Streptococcus pneumoniae in ceramide kinase-deficient mice.
Graf C, Zemann B, Rovina P, Urtz N, Schanzer A, Reuschel R, Mechtcheriakova D, Müller M, Fischer E, Reichel C, Huber S, Dawson J, Meingassner JG, Billich A, Niwa S, Badegruber R, Van Veldhoven PP, Kinzel B, Baumruker T, Bornancin F. Graf C, et al. Among authors: meingassner jg. J Immunol. 2008 Mar 1;180(5):3457-66. doi: 10.4049/jimmunol.180.5.3457. J Immunol. 2008. PMID: 18292572
76 results