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P-glycoprotein regulates trafficking of CD8(+) T cells to the brain parenchyma.
Kooij G, Kroon J, Paul D, Reijerkerk A, Geerts D, van der Pol SM, van Het Hof B, Drexhage JA, van Vliet SJ, Hekking LH, van Buul JD, Pachter JS, de Vries HE. Kooij G, et al. Among authors: reijerkerk a. Acta Neuropathol. 2014 May;127(5):699-711. doi: 10.1007/s00401-014-1244-8. Epub 2014 Jan 16. Acta Neuropathol. 2014. PMID: 24429546
T lymphocytes impair P-glycoprotein function during neuroinflammation.
Kooij G, van Horssen J, de Lange EC, Reijerkerk A, van der Pol SM, van Het Hof B, Drexhage J, Vennegoor A, Killestein J, Scheffer G, Oerlemans R, Scheper R, van der Valk P, Dijkstra CD, de Vries HE. Kooij G, et al. Among authors: reijerkerk a. J Autoimmun. 2010 Jun;34(4):416-25. doi: 10.1016/j.jaut.2009.10.006. Epub 2009 Dec 2. J Autoimmun. 2010. PMID: 19959334
P-glycoprotein acts as an immunomodulator during neuroinflammation.
Kooij G, Backer R, Koning JJ, Reijerkerk A, van Horssen J, van der Pol SM, Drexhage J, Schinkel A, Dijkstra CD, den Haan JM, Geijtenbeek TB, de Vries HE. Kooij G, et al. Among authors: reijerkerk a. PLoS One. 2009 Dec 8;4(12):e8212. doi: 10.1371/journal.pone.0008212. PLoS One. 2009. PMID: 19997559 Free PMC article.
Adenosine triphosphate-binding cassette transporters mediate chemokine (C-C motif) ligand 2 secretion from reactive astrocytes: relevance to multiple sclerosis pathogenesis.
Kooij G, Mizee MR, van Horssen J, Reijerkerk A, Witte ME, Drexhage JA, van der Pol SM, van Het Hof B, Scheffer G, Scheper R, Dijkstra CD, van der Valk P, de Vries HE. Kooij G, et al. Among authors: reijerkerk a. Brain. 2011 Feb;134(Pt 2):555-70. doi: 10.1093/brain/awq330. Epub 2010 Dec 22. Brain. 2011. PMID: 21183485
Fingolimod attenuates ceramide-induced blood-brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes.
van Doorn R, Nijland PG, Dekker N, Witte ME, Lopes-Pinheiro MA, van het Hof B, Kooij G, Reijerkerk A, Dijkstra C, van van der Valk P, van Horssen J, de Vries HE. van Doorn R, et al. Among authors: reijerkerk a. Acta Neuropathol. 2012 Sep;124(3):397-410. doi: 10.1007/s00401-012-1014-4. Epub 2012 Jul 19. Acta Neuropathol. 2012. PMID: 22810490
Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation.
Kooij G, Kopplin K, Blasig R, Stuiver M, Koning N, Goverse G, van der Pol SM, van Het Hof B, Gollasch M, Drexhage JA, Reijerkerk A, Meij IC, Mebius R, Willnow TE, Müller D, Blasig IE, de Vries HE. Kooij G, et al. Among authors: reijerkerk a. Acta Neuropathol. 2014 Aug;128(2):267-77. doi: 10.1007/s00401-013-1227-1. Epub 2013 Dec 20. Acta Neuropathol. 2014. PMID: 24356983
49 results