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CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.
Cartwright EK, Spicer L, Smith SA, Lee D, Fast R, Paganini S, Lawson BO, Nega M, Easley K, Schmitz JE, Bosinger SE, Paiardini M, Chahroudi A, Vanderford TH, Estes JD, Lifson JD, Derdeyn CA, Silvestri G. Cartwright EK, et al. Among authors: smith sa. Immunity. 2016 Sep 20;45(3):656-668. doi: 10.1016/j.immuni.2016.08.018. Immunity. 2016. PMID: 27653601 Free PMC article.
Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.
Kilgore KM, Murphy MK, Burton SL, Wetzel KS, Smith SA, Xiao P, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Hunter E, Collman RG, Amara RR, Derdeyn CA. Kilgore KM, et al. Among authors: smith sa. J Virol. 2015 Aug;89(16):8130-51. doi: 10.1128/JVI.01221-14. Epub 2015 May 27. J Virol. 2015. PMID: 26018167 Free PMC article.
Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses.
Burton SL, Kilgore KM, Smith SA, Reddy S, Hunter E, Robinson HL, Silvestri G, Amara RR, Derdeyn CA. Burton SL, et al. Among authors: smith sa. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10780-5. doi: 10.1073/pnas.1509731112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261312 Free PMC article.
A pathway to HIV-1 neutralization breadth.
Smith SA, Derdeyn CA. Smith SA, et al. Nat Med. 2015 Nov;21(11):1246-7. doi: 10.1038/nm.3989. Nat Med. 2015. PMID: 26540383 Free PMC article.
Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth.
Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, Allen S, Hunter E, Derdeyn CA. Smith SA, et al. PLoS Pathog. 2016 Nov 16;12(11):e1005989. doi: 10.1371/journal.ppat.1005989. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27851829 Free PMC article.
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G. McBrien JB, et al. Among authors: smith sa. Nature. 2020 Feb;578(7793):154-159. doi: 10.1038/s41586-020-1946-0. Epub 2020 Jan 22. Nature. 2020. PMID: 31969705 Free PMC article.
1,613 results