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Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia.
Guan Y, Greenberg EF, Hasipek M, Chen S, Liu X, Kerr CM, Gackowski D, Zarakowska E, Radivoyevitch T, Gu X, Willard B, Visconte V, Makishima H, Nazha A, Mukherji M, Sekeres MA, Saunthararajah Y, Oliński R, Xu M, Maciejewski JP, Jha BK. Guan Y, et al. Among authors: chen s. Commun Biol. 2020 Sep 7;3(1):493. doi: 10.1038/s42003-020-01220-9. Commun Biol. 2020. PMID: 32895473 Free PMC article.
Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.
Zhao Z, Chen L, Dawlaty MM, Pan F, Weeks O, Zhou Y, Cao Z, Shi H, Wang J, Lin L, Chen S, Yuan W, Qin Z, Ni H, Nimer SD, Yang FC, Jaenisch R, Jin P, Xu M. Zhao Z, et al. Among authors: chen l, chen s. Cell Rep. 2015 Nov 24;13(8):1692-704. doi: 10.1016/j.celrep.2015.10.037. Epub 2015 Nov 12. Cell Rep. 2015. PMID: 26586431 Free PMC article.
ASXL1 plays an important role in erythropoiesis.
Shi H, Yamamoto S, Sheng M, Bai J, Zhang P, Chen R, Chen S, Shi L, Abdel-Wahab O, Xu M, Zhou Y, Yang FC. Shi H, et al. Among authors: chen r, chen s. Sci Rep. 2016 Jun 29;6:28789. doi: 10.1038/srep28789. Sci Rep. 2016. PMID: 27352931 Free PMC article.
Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells.
Pan F, Wingo TS, Zhao Z, Gao R, Makishima H, Qu G, Lin L, Yu M, Ortega JR, Wang J, Nazha A, Chen L, Yao B, Liu C, Chen S, Weeks O, Ni H, Phillips BL, Huang S, Wang J, He C, Li GM, Radivoyevitch T, Aifantis I, Maciejewski JP, Yang FC, Jin P, Xu M. Pan F, et al. Among authors: chen l, chen s. Nat Commun. 2017 Apr 25;8:15102. doi: 10.1038/ncomms15102. Nat Commun. 2017. PMID: 28440315 Free PMC article.
Loss of Asxl2 leads to myeloid malignancies in mice.
Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, Williams S, Chen X, Wang QT, Nimer SD, Yu P, Wang QF, Xu M, Yang FC. Li J, et al. Among authors: chen s, chen x. Nat Commun. 2017 Jun 8;8:15456. doi: 10.1038/ncomms15456. Nat Commun. 2017. PMID: 28593990 Free PMC article.
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC).
Chu Y, Zhao Z, Sant DW, Zhu G, Greenblatt SM, Liu L, Wang J, Cao Z, Tho JC, Chen S, Liu X, Zhang P, Maciejewski JP, Nimer S, Wang G, Yuan W, Yang FC, Xu M. Chu Y, et al. Among authors: chen s. Genomics Proteomics Bioinformatics. 2018 Jun;16(3):172-186. doi: 10.1016/j.gpb.2018.04.005. Epub 2018 Jun 13. Genomics Proteomics Bioinformatics. 2018. PMID: 29908294 Free PMC article.
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